Template:Glucocorticoid activity of selected steroids in vitro
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Steroid | Class | TR (↑)a | GR (%)b |
---|---|---|---|
Template:No selflink | Corticosteroid | ++ | 100 |
Template:No selflink | Estrogen | – | 0 |
Template:No selflink | Progestin | + | 14 |
Template:No selflink | Progestin | + | 27 |
Template:No selflink | Progestin | – | 1 |
Template:No selflink | Progestin | + | 29 |
Template:No selflink | Progestin | – | 0 |
Template:No selflink | Progestin | – | 1 |
Template:No selflink | Progestogen | + | 10 |
Footnotes: a = Thrombin receptor (TR) upregulation (↑) in vascular smooth muscle cells (VSMCs). b = RBA (%) for the glucocorticoid receptor (GR). Strength: – = No effect. + = Pronounced effect. ++ = Strong effect. Sources: [1] |
References
- ↑ Kuhl H (2005). "Pharmacology of estrogens and progestogens: influence of different routes of administration" (PDF). Climacteric. 8 Suppl 1: 3–63. doi:10.1080/13697130500148875. PMID 16112947. S2CID 24616324.