Template:Androgen replacement therapy formulations and dosages used in men

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Androgen replacement therapy formulations and dosages used in men

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Route Medication Major brand names Form Dosage
Oral Template:No selflinka Tablet 400–800 mg/day (in divided doses)
Template:No selflink Andriol, Jatenzo Capsule 40–80 mg/2–4x day (with meals)
Template:No selflinkb Android, Metandren, Testred Tablet 10–50 mg/day
Template:No selflinkb Halotestin, Ora-Testryl, Ultandren Tablet 5–20 mg/day
Template:No selflinkb Dianabol Tablet 5–15 mg/day
Template:No selflinkb Proviron Tablet 25–150 mg/day
Buccal Template:No selflink Striant Tablet 30 mg 2x/day
Template:No selflinkb Metandren, Oreton Methyl Tablet 5–25 mg/day
Sublingual Template:No selflinkb Testoral Tablet 5–10 mg 1–4x/day
Template:No selflinkb Metandren, Oreton Methyl Tablet 10–30 mg/day
Intranasal Template:No selflink Natesto Nasal spray 11 mg 3x/day
Transdermal Template:No selflink AndroGel, Testim, TestoGel Gel 25–125 mg/day
Androderm, AndroPatch, TestoPatch Non-scrotal patch 2.5–15 mg/day
Testoderm Scrotal patch 4–6 mg/day
Axiron Axillary solution 30–120 mg/day
Template:No selflink Andractim Gel 100–250 mg/day
Rectal Template:No selflink Rektandron, Testosteronb Suppository 40 mg 2–3x/day
Injection (IM or SC) Template:No selflink Andronaq, Sterotate, Virosterone Aqueous suspension 10–50 mg 2–3x/week
Template:No selflinkb Testoviron Oil solution 10–50 mg 2–3x/week
Template:No selflink Delatestryl Oil solution 50–250 mg 1x/1–4 weeks
Xyosted Auto-injector 50–100 mg 1x/week
Template:No selflink Depo-Testosterone Oil solution 50–250 mg 1x/1–4 weeks
Template:No selflink Agovirin Depot Aqueous suspension 50–100 mg 1x/1–2 weeks
Template:No selflinkb Perandren, Androject Oil solution 50–200 mg 1x/3–5 weeks
Template:No selflink Sustanon 100, Sustanon 250 Oil solution 50–250 mg 1x/2–4 weeks
Template:No selflink Aveed, Nebido Oil solution 750–1,000 mg 1x/10–14 weeks
Template:No selflinka Aqueous suspension 600–1,000 mg 1x/12–20 weeks
Implant Template:No selflink Testopel Pellet 150–1,200 mg/3–6 months
Notes: Men produce about 3 to 11 mg testosterone per day (mean 7 mg/day in young men). Footnotes: a = Never marketed. b = No longer used and/or no longer marketed. Sources: [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37]
Template documentation

See also

References

  1. Eberhard Nieschlag; Hermann M. Behre (6 December 2012). Testosterone: Action - Deficiency - Substitution. Springer Science & Business Media. pp. 298–. ISBN 978-3-642-72185-4.
  2. Eberhard Nieschlag; Hermann M. Behre; Susan Nieschlag (26 July 2012). Testosterone: Action, Deficiency, Substitution. Cambridge University Press. pp. 312–. ISBN 978-1-107-01290-5.
  3. Eberhard Nieschlag; Hermann M. Behre; Susan Nieschlag (13 January 2010). Andrology: Male Reproductive Health and Dysfunction. Springer Science & Business Media. pp. 443–. ISBN 978-3-540-78355-8.
  4. Byrne, M. M.; Nieschlag, E. (2017). "Androgens: Pharmacological Use and Abuse". Encyclopedia of Hormones. doi:10.1016/B978-0-12-809324-5.03356-3.
  5. Eberhard Nieschlag; Hermann Behre (29 June 2013). Andrology: Male Reproductive Health and Dysfunction. Springer Science & Business Media. p. 444. ISBN 978-3-662-04491-9.
  6. Alexandre Hohl (30 March 2017). Testosterone: From Basic to Clinical Aspects. Springer. pp. 143, 175–177, 204–206, 229, 241, 255. ISBN 978-3-319-46086-4.
  7. Wayne J.G. Hellstrom (28 November 2012). Androgen Deficiency and Testosterone Replacement: Current Controversies and Strategies. Springer Science & Business Media. pp. 91, 129–139. ISBN 978-1-62703-179-0.
  8. Malcolm Carruthers (2006). Androgen Deficiency in the Adult Male: Causes, Diagnosis and Treatment. CRC Press. pp. 137–178. ISBN 978-0-367-80018-5.
  9. Carrie Bagatell; William J. Bremner (27 May 2003). Androgens in Health and Disease. Springer Science & Business Media. pp. 141–153, 200–202, 313–334, 359, 384, 403, 430–431. ISBN 978-1-59259-388-0.
  10. William Llewellyn (2011). Anabolics. Molecular Nutrition Llc. pp. 11, 28–33, 321, 370, 385, 392, 394, 397, 412, 433, 506, 537, 678. ISBN 978-0-9828280-1-4.
  11. Nieschlag, E.; Freischem, C. W. (1982). "Androgen Therapy in Hypogonadism and Infertility". In J. Bain; Wolf-Bernhard Schill; L. Schwarzstein (eds.). Treatment of Male Infertility. pp. 103–115. doi:10.1007/978-3-642-68223-0_8. ISBN 978-3-642-68223-0.
  12. T. Hugh Jones (2009). Advances in the Management of Testosterone Deficiency. Karger Medical and Scientific Publishers. pp. 32–51, 140–141, 144. ISBN 978-3-8055-8622-1.
  13. Alan J. Wein; Louis R. Kavoussi; Andrew C. Novick; Alan W. Partin, Craig A. Peters (28 September 2011). Campbell-Walsh Urology. Elsevier Health Sciences. pp. 739–740. ISBN 1-4557-2298-7.
  14. Snyder, P J (1984). "Clinical Use of Androgens". Annual Review of Medicine. 35 (1): 207–217. doi:10.1146/annurev.me.35.020184.001231. ISSN 0066-4219.
  15. Manuchair Ebadi (31 October 2007). Desk Reference of Clinical Pharmacology. CRC Press. pp. 434–. ISBN 978-1-4200-4744-8.
  16. Charles D. Kochakian (6 December 2012). Anabolic-Androgenic Steroids. Springer Science & Business Media. pp. 454–. ISBN 978-3-642-66353-6.
  17. Basaria, Shehzad; Wahlstrom, Justin T.; Dobs, Adrian S. (2001). "Anabolic-Androgenic Steroid Therapy in the Treatment of Chronic Diseases". The Journal of Clinical Endocrinology & Metabolism. 86 (11): 5108–5117. doi:10.1210/jcem.86.11.7983. ISSN 0021-972X.
  18. Srinivas-Shankar, U.; Sharma, D. (2009). "Testosterone treatment in elderly men". Advances in Therapy. 26 (1): 25–39. doi:10.1007/s12325-008-0137-4. ISSN 0741-238X.
  19. Wang, Christina; Swerdloff, Ronald S. (1997). "Androgen Replacement Therapy". Annals of Medicine. 29 (5): 365–370. doi:10.3109/07853899708999363. ISSN 0785-3890.
  20. Morales, A.; Lunenfeld, B. (2009). "Androgen replacement therapy in aging men with secondary hypogonadism". The Aging Male. 4 (3): 151–162. doi:10.1080/tam.4.3.151.162. ISSN 1368-5538.
  21. Srinivas-Shankar, Upendram; Wu, Frederick CW (2006). "Drug Insight: testosterone preparations". Nature Clinical Practice Urology. 3 (12): 653–665. doi:10.1038/ncpuro0650. ISSN 1743-4270.
  22. Tan, Robert S.; Bransgrove, Linda (2015). "Testosterone replacement therapy". Postgraduate Medicine. 103 (5): 247–256. doi:10.3810/pgm.1998.05.491. ISSN 0032-5481.
  23. Zitzmann, M; Nieschlag, E (2000). "Hormone substitution in male hypogonadism". Molecular and Cellular Endocrinology. 161 (1–2): 73–88. doi:10.1016/S0303-7207(99)00227-0. ISSN 0303-7207.
  24. Kaufman, Joel M. (2004). "Evolution of delivery systems for testosterone administration". Current Sexual Health Reports. 1 (3): 109–114. doi:10.1007/s11930-004-0025-0. ISSN 1548-3584.
  25. Leichtnam, Marie-Laure; Rolland, Hervé; Wüthrich, Patrick; Guy, Richard H. (2006). "Testosterone Hormone Replacement Therapy: State-of-the-Art and Emerging Technologies". Pharmaceutical Research. 23 (6): 1117–1132. doi:10.1007/s11095-006-0072-5. ISSN 0724-8741.
  26. Morales, Alvaro (2005). "Androgen replacement therapy in the hypogonadal ageing man". Expert Opinion on Pharmacotherapy. 4 (6): 911–918. doi:10.1517/14656566.4.6.911. ISSN 1465-6566.
  27. Byrne, M. M.; Nieschlag, E. (2014). "Testosterone replacement therapy in male hypogonadism". Journal of Endocrinological Investigation. 26 (5): 481–489. doi:10.1007/BF03345206. ISSN 0391-4097.
  28. Yassin AA, Haffejee M (2007). "Testosterone depot injection in male hypogonadism: a critical appraisal". Clin Interv Aging. 2 (4): 577–90. PMC 2686335. PMID 18225458.
  29. Nieschlag, Eberhard (2015). "Current topics in testosterone replacement of hypogonadal men". Best Practice & Research Clinical Endocrinology & Metabolism. 29 (1): 77–90. doi:10.1016/j.beem.2014.09.008. ISSN 1521-690X.
  30. Gooren, Louis J G; Bunck, Mathijs C M (2004). "Androgen Replacement Therapy". Drugs. 64 (17): 1861–1891. doi:10.2165/00003495-200464170-00002. ISSN 0012-6667.
  31. Surampudi, Prasanth; Swerdloff, Ronald S; Wang, Christina (2014). "An update on male hypogonadism therapy". Expert Opinion on Pharmacotherapy. 15 (9): 1247–1264. doi:10.1517/14656566.2014.913022. ISSN 1465-6566.
  32. Buvat, Jacques; Maggi, Mario; Guay, André; Torres, Luiz Otavio (2013). "Testosterone Deficiency in Men: Systematic Review and Standard Operating Procedures for Diagnosis and Treatment". The Journal of Sexual Medicine. 10 (1): 245–284. doi:10.1111/j.1743-6109.2012.02783.x. ISSN 1743-6095.
  33. Hafez, B.; Hafez, E. S. E. (2009). "Andropause: Endocrinology, Erectile Dysfunction, and Prostate Pathophysiology". Archives of Andrology. 50 (2): 45–68. doi:10.1080/aan.50.2.45.68. ISSN 0148-5016.
  34. Llahana, Sofia (2019). "Testosterone Therapy in Adult Men with Hypogonadism". Advanced Practice in Endocrinology Nursing. pp. 885–902. doi:10.1007/978-3-319-99817-6_46.
  35. Lunenfeld, Bruno; Oettel, Michael (2009). "Therapeutic potential of testosterone gels". Aging Health. 5 (2): 227–245. doi:10.2217/ahe.09.6. ISSN 1745-509X.
  36. Janet Brotherton (1976). Sex Hormone Pharmacology. Academic Press. pp. 18–19, 331, 336. ISBN 978-0-12-137250-7.
  37. Geraline C. Lin; Lynda Erinoff (July 1996). Anabolic Steroid Abuse. DIANE Publishing. pp. 144–. ISBN 978-0-7881-2969-8.